2R75

Aquifex aeolicus FtsZ with 8-morpholino-GTP

Summary for 2R75

Entry DOI	10.2210/pdb2r75/pdb
Related	2R6R
Descriptor	Cell division protein ftsZ, MAGNESIUM ION, 8-morpholin-4-ylguanosine 5'-(tetrahydrogen triphosphate), ... (4 entities in total)
Functional Keywords	gtpase, tubulin-like, inhibitor, cell cycle
Biological source	Aquifex aeolicus
Cellular location	Cytoplasm (By similarity): O66809
Total number of polymer chains	1
Total formula weight	37461.81
Authors	Lappchen, T.,Pinas, V.A.,Hartog, A.F.,Koomen, G.J.,Schaffner-Barbero, C.,Andreu, J.M.,Trambaiolo, D.,Lowe, J.,Juhem, A.,Popov, A.V.,den Blaauwen, T. (deposition date: 2007-09-07, release date: 2008-07-22, Last modification date: 2023-08-30)
Primary citation	Lappchen, T.,Pinas, V.A.,Hartog, A.F.,Koomen, G.J.,Schaffner-Barbero, C.,Andreu, J.M.,Trambaiolo, D.,Lowe, J.,Juhem, A.,Popov, A.V.,den Blaauwen, T. Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites Chem.Biol., 15:189-199, 2008 Cited by PubMed: 18291323 DOI: 10.1016/j.chembiol.2007.12.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.402 Å)

Structure validation