2R2O

Crystal structure of the effector domain of human Plexin B1

2R2O の概要

• エントリーDOI: 10.2210/pdb2r2o/pdb
• 分子名称: Plexin-B1, UNKNOWN ATOM OR ION (3 entities in total)
• 機能のキーワード: plexin, effector domain, structural genomics, structural genomics consortium, sgc, glycoprotein, membrane, phosphorylation, receptor, secreted, transmembrane, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted: O43157
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31068.52

構造登録者

Tong, Y.,Tempel, W.,Shen, L.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2007-08-27, 公開日: 2007-09-04, 最終更新日: 2017-10-25)

• 主引用文献: Tong, Y.,Chugha, P.,Hota, P.K.,Alviani, R.S.,Li, M.,Tempel, W.,Shen, L.,Park, H.W.,Buck, M.; Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.; J.Biol.Chem., 282:37215-37224, 2007; PubMed: 17916560; DOI: 10.1074/jbc.M703800200

実験手法

X-RAY DIFFRACTION (2 Å)