Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required

Summary for 2QRZ

DescriptorCell division control protein 42 homolog precursor, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsg-domain fold, g protein, gtpase, alternative splicing, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, cell cycle
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P60953
Total number of polymer chains2
Total molecular weight43301.62
Phillips, M.J.,Calero, G.,Chan, B.,Cerione, R.A. (deposition date: 2007-07-30, release date: 2008-03-18, Last modification date: 2011-07-13)
Primary citation
Phillips, M.J.,Calero, G.,Chan, B.,Ramachandran, S.,Cerione, R.A.
Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42.
J.Biol.Chem., 283:14153-14164, 2008
PubMed: 18348980 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M706271200
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.233171.4%3.6%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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