2QRZ

Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required

Summary for 2QRZ

• Entry DOI: 10.2210/pdb2qrz/pdb
• Descriptor: Cell division control protein 42 homolog precursor, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: g-domain fold, g protein, gtpase, alternative splicing, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, cell cycle
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953
• Total number of polymer chains: 2
• Total formula weight: 43301.62

Authors

Phillips, M.J.,Calero, G.,Chan, B.,Cerione, R.A. (deposition date: 2007-07-30, release date: 2008-03-18, Last modification date: 2011-07-13)

• Primary citation: Phillips, M.J.,Calero, G.,Chan, B.,Ramachandran, S.,Cerione, R.A.; Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42.; J.Biol.Chem., 283:14153-14164, 2008; PubMed: 18348980; DOI: 10.1074/jbc.M706271200

Experimental method

X-RAY DIFFRACTION (2.4 Å)