2QRZ

Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required

2QRZ の概要

• エントリーDOI: 10.2210/pdb2qrz/pdb
• 分子名称: Cell division control protein 42 homolog precursor, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: g-domain fold, g protein, gtpase, alternative splicing, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, cell cycle
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43301.62

構造登録者

Phillips, M.J.,Calero, G.,Chan, B.,Cerione, R.A. (登録日: 2007-07-30, 公開日: 2008-03-18, 最終更新日: 2011-07-13)

• 主引用文献: Phillips, M.J.,Calero, G.,Chan, B.,Ramachandran, S.,Cerione, R.A.; Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42.; J.Biol.Chem., 283:14153-14164, 2008; PubMed: 18348980; DOI: 10.1074/jbc.M706271200

実験手法

X-RAY DIFFRACTION (2.4 Å)