2QP3

Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1

Summary for 2QP3

Entry DOI	10.2210/pdb2qp3/pdb
Related	2QP4
Descriptor	Bile salt sulfotransferase, (3Beta,5alpha)-3-Hydroxyandrostan-17-one (2 entities in total)
Functional Keywords	dehydroepiandrosterone(dhea), androsterone(adt), substrate inhibition, sulfotransferase, substrate binding orientation, bile acid catabolism, lipid metabolism, steroid metabolism, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q06520
Total number of polymer chains	1
Total formula weight	33992.01
Authors	Hsieh, Y.C. (deposition date: 2007-07-23, release date: 2008-07-29, Last modification date: 2024-05-29)
Primary citation	Lu, L.Y.,Hsieh, Y.C.,Liu, M.Y.,Lin, Y.H.,Chen, C.J.,Yang, Y.S. Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1) Mol.Pharmacol., 73:660-668, 2008 Cited by PubMed: 18042734 DOI: 10.1124/mol.107.041038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation