2QP3
Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1
Summary for 2QP3
Entry DOI | 10.2210/pdb2qp3/pdb |
Related | 2QP4 |
Descriptor | Bile salt sulfotransferase, (3Beta,5alpha)-3-Hydroxyandrostan-17-one (2 entities in total) |
Functional Keywords | dehydroepiandrosterone(dhea), androsterone(adt), substrate inhibition, sulfotransferase, substrate binding orientation, bile acid catabolism, lipid metabolism, steroid metabolism, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q06520 |
Total number of polymer chains | 1 |
Total formula weight | 33992.01 |
Authors | Hsieh, Y.C. (deposition date: 2007-07-23, release date: 2008-07-29, Last modification date: 2024-05-29) |
Primary citation | Lu, L.Y.,Hsieh, Y.C.,Liu, M.Y.,Lin, Y.H.,Chen, C.J.,Yang, Y.S. Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1) Mol.Pharmacol., 73:660-668, 2008 Cited by PubMed: 18042734DOI: 10.1124/mol.107.041038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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