2QLF
Crystal Structure of Caspase-7 with inhibitor AC-DNLD-CHO
Summary for 2QLF
Entry DOI | 10.2210/pdb2qlf/pdb |
Related | 2QL5 2QL7 2QL9 2QLB 2QLJ |
Related PRD ID | PRD_000282 |
Descriptor | Caspase-7, Inhibitor AC-DNLD-CHO, Peptide QGHGE, ... (5 entities in total) |
Functional Keywords | cysteine protease, apoptosis, thiol protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P55210 P55210 |
Total number of polymer chains | 7 |
Total formula weight | 63337.44 |
Authors | Agniswamy, J.,Fang, B.,Weber, I. (deposition date: 2007-07-12, release date: 2007-08-28, Last modification date: 2023-11-15) |
Primary citation | Agniswamy, J.,Fang, B.,Weber, I.T. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274:4752-4765, 2007 Cited by PubMed: 17697120DOI: 10.1111/j.1742-4658.2007.05994.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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