2QFJ
Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE
Summary for 2QFJ
| Entry DOI | 10.2210/pdb2qfj/pdb |
| Descriptor | DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor (3 entities in total) |
| Functional Keywords | protein-dna complex, rrm domains, transcription repressor-dna complex, transcription repressor/dna |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 54514.03 |
| Authors | Crichlow, G.V.,Yang, Y.,Fan, C.,Lolis, E.,Braddock, D. (deposition date: 2007-06-27, release date: 2008-03-04, Last modification date: 2024-02-21) |
| Primary citation | Crichlow, G.V.,Zhou, H.,Hsiao, H.-H.,Frederick, K.B.,Debrosse, M.,Yang, Y.,Folta-Stogniew, E.J.,Chung, H.-J.,Fan, C.,De La Cruz, E.M.,Levens, D.,Lolis, E.,Braddock, D. Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition EMBO J., 27:277-289, 2007 Cited by PubMed: 18059478DOI: 10.1038/sj.emboj.7601936 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
