2QFG

Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H.

2QFG の概要

• エントリーDOI: 10.2210/pdb2qfg/pdb
• 関連するPDBエントリー: 1haq 2QFH
• 分子名称: Complement factor H (1 entity in total)
• 機能のキーワード: x-ray scattering, complement, scr domain, factor h, age-related macular degeneration, complement alternate pathway, disease mutation, glycoprotein, immune response, innate immunity, sushi, immune system
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P08603
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35434.67

構造登録者

Okemefuna, A.I.,Gilbert, H.E.,Griggs, K.M.,Ormsby, R.J.,Gordon, D.L.,Perkins, S.J. (登録日: 2007-06-27, 公開日: 2007-09-25, 最終更新日: 2024-02-21)

• 主引用文献: Okemefuna, A.I.,Gilbert, H.E.,Griggs, K.M.,Ormsby, R.J.,Gordon, D.L.,Perkins, S.J.; The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.; J.Mol.Biol., 375:80-101, 2008; PubMed: 18005991; DOI: 10.1016/j.jmb.2007.09.026

実験手法

SOLUTION SCATTERING