2QEF

X-ray structure of 7-deaza-dG and Z3dU modified duplex CGCGAATXCZCG

Summary for 2QEF

• Entry DOI: 10.2210/pdb2qef/pdb
• Related: 2QEG
• Descriptor: DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*(ZDU)P*DCP*(7GU)P*DCP*DG)-3') (2 entities in total)
• Functional Keywords: b-dna, z3du, 7-deaza-dg, dna
• Total number of polymer chains: 2
• Total formula weight: 7410.94

Authors

Wang, F.,Li, F.,Ganguly, M.,Marky, L.A.,Gold, B.,Egli, M.,Stone, M.P. (deposition date: 2007-06-25, release date: 2008-05-06, Last modification date: 2023-08-30)

• Primary citation: Wang, F.,Li, F.,Ganguly, M.,Marky, L.A.,Gold, B.,Egli, M.,Stone, M.P.; A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.; Biochemistry, 47:7147-7157, 2008; PubMed: 18549246; DOI: 10.1021/bi800375m

Experimental method

X-RAY DIFFRACTION (1.6 Å)