2Q1Q
Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies
Summary for 2Q1Q
Entry DOI | 10.2210/pdb2q1q/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | antiepileptic, carbonic anhydrase, inhibitors, lyase |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29845.42 |
Authors | Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T. (deposition date: 2007-05-25, release date: 2007-09-11, Last modification date: 2024-02-21) |
Primary citation | Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 17:4866-4872, 2007 Cited by PubMed: 17588751DOI: 10.1016/j.bmcl.2007.06.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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