2Q1Q

Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies

2Q1Q の概要

• エントリーDOI: 10.2210/pdb2q1q/pdb
• 分子名称: Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
• 機能のキーワード: antiepileptic, carbonic anhydrase, inhibitors, lyase
• 細胞内の位置: Cytoplasm : P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29845.42

構造登録者

Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T. (登録日: 2007-05-25, 公開日: 2007-09-11, 最終更新日: 2024-02-21)

• 主引用文献: Temperini, C.,Innocenti, A.,Mastrolorenzo, A.,Scozzafava, A.,Supuran, C.T.; Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies.; Bioorg.Med.Chem.Lett., 17:4866-4872, 2007; PubMed: 17588751; DOI: 10.1016/j.bmcl.2007.06.044

実験手法

X-RAY DIFFRACTION (1.9 Å)