2PV7

Crystal structure of chorismate mutase / prephenate dehydrogenase (tyrA) (1574749) from Haemophilus influenzae RD at 2.00 A resolution

Summary for 2PV7

• Entry DOI: 10.2210/pdb2pv7/pdb
• Descriptor: T-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM) and Prephenate dehydrogenase (EC 1.3.1.12) (PDH)], TYROSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• Functional Keywords: 1574749, chorismate mutase type ii, chorismate mutase / prephenate dehydrogenase (tyra), structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, isomerase, oxidoreductase
• Biological source: Haemophilus influenzae
• Cellular location: Cytoplasm: P43902
• Total number of polymer chains: 2
• Total formula weight: 70240.84

Authors

Joint Center for Structural Genomics (JCSG) (deposition date: 2007-05-09, release date: 2007-05-22, Last modification date: 2023-01-25)

• Primary citation: Chiu, H.J.,Abdubek, P.,Astakhova, T.,Axelrod, H.L.,Carlton, D.,Clayton, T.,Das, D.,Deller, M.C.,Duan, L.,Feuerhelm, J.,Grant, J.C.,Grzechnik, A.,Han, G.W.,Jaroszewski, L.,Jin, K.K.,Klock, H.E.,Knuth, M.W.,Kozbial, P.,Krishna, S.S.,Kumar, A.,Marciano, D.,McMullan, D.,Miller, M.D.,Morse, A.T.,Nigoghossian, E.,Okach, L.,Reyes, R.,Tien, H.J.,Trame, C.B.,van den Bedem, H.,Weekes, D.,Xu, Q.,Hodgson, K.O.,Wooley, J.,Elsliger, M.A.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A.; The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.; Acta Crystallogr.,Sect.F, 66:1317-1325, 2010; PubMed: 20944228; DOI: 10.1107/S1744309110021688

Experimental method

X-RAY DIFFRACTION (2 Å)