2PUG

CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES

2PUG の概要

• エントリーDOI: 10.2210/pdb2pug/pdb
• 分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE, ... (4 entities in total)
• 機能のキーワード: complex (dna-binding protein-dna), dna-binding regulatory protein, extended corepressor specificity, transcription-dna complex, transcription/dna
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43401.03

構造登録者

Lu, F.,Schumacher, M.A.,Arvidson, D.N.,Haldimann, A.,Wanner, B.L.,Zalkin, H.,Brennan, R.G. (登録日: 1997-10-04, 公開日: 1998-05-06, 最終更新日: 2024-02-21)

• 主引用文献: Lu, F.,Schumacher, M.A.,Arvidson, D.N.,Haldimann, A.,Wanner, B.L.,Zalkin, H.,Brennan, R.G.; Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.; Biochemistry, 37:971-982, 1998; PubMed: 9454587; DOI: 10.1021/bi971942s

実験手法

X-RAY DIFFRACTION (2.7 Å)