2PNT
Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1
Summary for 2PNT
Entry DOI | 10.2210/pdb2pnt/pdb |
Descriptor | General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION (3 entities in total) |
Functional Keywords | scaffold protein, structural genomics, structural genomics consortium, sgc, unknown function |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, perinuclear region : Q7Z6J2 |
Total number of polymer chains | 2 |
Total formula weight | 22140.39 |
Authors | Elkins, J.,Papagrigoriou, E.,Cooper, C.,Gileadi, C.,Uppenberg, J.,Bray, J.,von Delft, F.,Pike, A.C.W.,Ugochukwu, E.,Umeano, C.,Gileadi, O.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2007-04-25, release date: 2007-05-08, Last modification date: 2023-08-30) |
Primary citation | Elkins, J.M.,Gileadi, C.,Shrestha, L.,Phillips, C.,Wang, J.,Muniz, J.R.,Doyle, D.A. Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms Protein Sci., 19:731-741, 2010 Cited by PubMed: 20120020DOI: 10.1002/pro.349 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.148 Å) |
Structure validation
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