2PKT

Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1

Summary for 2PKT

• Entry DOI: 10.2210/pdb2pkt/pdb
• Descriptor: PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: pdz domain, structural genomics, structural genomics consortium, sgc, unknown function
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : O00151
• Total number of polymer chains: 1
• Total formula weight: 10207.87

Authors

Uppenberg, J.,Gileadi, C.,Elkins, J.,Bray, J.,Burgess-Brown, N.,Salah, E.,Gileadi, O.,Bunkoczi, G.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2007-04-18, release date: 2007-05-08, Last modification date: 2024-04-03)

• Primary citation: Elkins, J.M.,Gileadi, C.,Shrestha, L.,Phillips, C.,Wang, J.,Muniz, J.R.,Doyle, D.A.; Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms; Protein Sci., 19:731-741, 2010; PubMed: 20120020; DOI: 10.1002/pro.349

Experimental method

X-RAY DIFFRACTION (1.5 Å)