2PD3

Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan

Replaces:  1JVF

Summary for 2PD3

• Entry DOI: 10.2210/pdb2pd3/pdb
• Related: 2PD4
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total)
• Functional Keywords: antibacterial target, helicobacter pylori, type ii fatty acid biosynthesis, enoyl-acp-reductase, fabi, oxidoreductase
• Biological source: Helicobacter pylori
• Total number of polymer chains: 4
• Total formula weight: 123877.56

Authors

Lee, H.H.,Moon, J.H.,Suh, S.W. (deposition date: 2007-03-31, release date: 2007-04-17, Last modification date: 2023-10-25)

• Primary citation: Lee, H.H.,Moon, J.H.,Suh, S.W.; Crystal structure of the Helicobacter pylori enoyl-acyl carrier protein reductase in complex with hydroxydiphenyl ether compounds, triclosan and diclosan; Proteins, 69:691-694, 2007; PubMed: 17879346; DOI: 10.1002/prot.21586

Experimental method

X-RAY DIFFRACTION (2.5 Å)