2PA1
Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin
Summary for 2PA1
Entry DOI | 10.2210/pdb2pa1/pdb |
Descriptor | PDZ and LIM domain protein 2, CHLORIDE ION (3 entities in total) |
Functional Keywords | pdz domain, structural genomics, structural genomics consortium, sgc, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm . Isoform 1: Cytoplasm, cytoskeleton. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Nucleus: Q96JY6 |
Total number of polymer chains | 1 |
Total formula weight | 9419.63 |
Authors | Uppenberg, J.,Shrestha, L.,Elkins, J.,Burgess-Brown, N.,Salah, E.,Bunkoczi, G.,Papagrigoriou, E.,Pike, A.C.W.,Turnbull, A.P.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2007-03-27, release date: 2007-05-01, Last modification date: 2024-04-03) |
Primary citation | Elkins, J.M.,Gileadi, C.,Shrestha, L.,Phillips, C.,Wang, J.,Muniz, J.R.,Doyle, D.A. Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms Protein Sci., 19:731-741, 2010 Cited by PubMed: 20120020DOI: 10.1002/pro.349 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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