2PA1

Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin

2PA1 の概要

• エントリーDOI: 10.2210/pdb2pa1/pdb
• 分子名称: PDZ and LIM domain protein 2, CHLORIDE ION (3 entities in total)
• 機能のキーワード: pdz domain, structural genomics, structural genomics consortium, sgc, metal binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm . Isoform 1: Cytoplasm, cytoskeleton. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Nucleus: Q96JY6
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9419.63

構造登録者

Uppenberg, J.,Shrestha, L.,Elkins, J.,Burgess-Brown, N.,Salah, E.,Bunkoczi, G.,Papagrigoriou, E.,Pike, A.C.W.,Turnbull, A.P.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (登録日: 2007-03-27, 公開日: 2007-05-01, 最終更新日: 2024-04-03)

• 主引用文献: Elkins, J.M.,Gileadi, C.,Shrestha, L.,Phillips, C.,Wang, J.,Muniz, J.R.,Doyle, D.A.; Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms; Protein Sci., 19:731-741, 2010; PubMed: 20120020; DOI: 10.1002/pro.349

実験手法

X-RAY DIFFRACTION (1.7 Å)