2P7F

The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme

Summary for 2P7F

Entry DOI	10.2210/pdb2p7f/pdb
Related	2OUE 2P7D 2P7E
Descriptor	substrate strand, Loop A ribozyme strand, Loop B ribozyme strand, ... (7 entities in total)
Functional Keywords	hairpin ribozyme; 2', 5' phosphodiester; vanadate; reaction intermediate; transition-state stabilization; active site waters; induced fit, rna
Total number of polymer chains	4
Total formula weight	19952.23
Authors	Torelli, A.T.,Krucinska, J.,Wedekind, J.E. (deposition date: 2007-03-20, release date: 2007-05-22, Last modification date: 2023-08-30)
Primary citation	Torelli, A.T.,Krucinska, J.,Wedekind, J.E. A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization Rna, 13:1052-1070, 2007 Cited by PubMed: 17488874 DOI: 10.1261/rna.510807 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation