2P7F

The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme

2P7F の概要

• エントリーDOI: 10.2210/pdb2p7f/pdb
• 関連するPDBエントリー: 2OUE 2P7D 2P7E
• 分子名称: substrate strand, Loop A ribozyme strand, Loop B ribozyme strand, ... (7 entities in total)
• 機能のキーワード: hairpin ribozyme; 2', 5' phosphodiester; vanadate; reaction intermediate; transition-state stabilization; active site waters; induced fit, rna
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 19952.23

構造登録者

Torelli, A.T.,Krucinska, J.,Wedekind, J.E. (登録日: 2007-03-20, 公開日: 2007-05-22, 最終更新日: 2023-08-30)

• 主引用文献: Torelli, A.T.,Krucinska, J.,Wedekind, J.E.; A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization; Rna, 13:1052-1070, 2007; PubMed: 17488874; DOI: 10.1261/rna.510807

実験手法

X-RAY DIFFRACTION (2.35 Å)