2P7C

Solution structure of the bacillus licheniformis BlaI monomeric form in complex with the blaP half-operator.

2P7C の概要

• エントリーDOI: 10.2210/pdb2p7c/pdb
• NMR情報: BMRB: 5873
• 分子名称: Strand 1 of Twelve base-pair DNA, Strand 2 of Twelve base-pair DNA, Penicillinase repressor (3 entities in total)
• 機能のキーワード: protein-dna complex, repressor, monomer, operator, antibiotics, transcription regulator
• 由来する生物種: Bacillus licheniformis; 詳細
• 細胞内の位置: Cytoplasm (Probable): P06555
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 16832.93

構造登録者

Boudet, J.,Duval, V.,Van Melckebeke, H.,Blackledge, M.,Amoroso, A.,Joris, B.,Simorre, J.-P. (登録日: 2007-03-20, 公開日: 2007-06-12, 最終更新日: 2024-05-22)

• 主引用文献: Boudet, J.,Duval, V.,Van Melckebeke, H.,Blackledge, M.,Amoroso, A.,Joris, B.,Simorre, J.P.; Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against beta-lactam antibiotics.; Nucleic Acids Res., 35:4384-4395, 2007; PubMed: 17576674; DOI: 10.1093/nar/gkm448

実験手法

SOLUTION NMR