2P46
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: se5b-ortho-2 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
2P46 の概要
エントリーDOI | 10.2210/pdb2p46/pdb |
分子名称 | Ribonuclease pancreatic, ANTIBODY CAB-RN05, ZINC ION, ... (4 entities in total) |
機能のキーワード | semet phasing, camelid single-domain antibody, vhh, cab-rn05, rnase a, yeast surface display, hydrolase-immune system complex, hydrolase/immune system |
由来する生物種 | Camelus dromedarius (Arabian camel) 詳細 |
細胞内の位置 | Secreted: P61823 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 54818.15 |
構造登録者 | Tereshko, V.,Uysal, S.,Koide, A.,Margalef, K.,Koide, S.,Kossiakoff, A.A. (登録日: 2007-03-11, 公開日: 2008-03-11, 最終更新日: 2011-07-13) |
主引用文献 | Tereshko, V.,Uysal, S.,Koide, A.,Margalef, K.,Koide, S.,Kossiakoff, A.A. Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17:1175-1187, 2008 Cited by PubMed: 18445622DOI: 10.1110/ps.034892.108 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.5 Å) |
構造検証レポート
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