2P3F

Crystal structure of the factor Xa/NAP5 complex

Summary for 2P3F

• Entry DOI: 10.2210/pdb2p3f/pdb
• Descriptor: Coagulation factor X, Anti-coagulant protein 5, SODIUM ION, ... (5 entities in total)
• Functional Keywords: factor xa, nematode anticoagulant protein, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 3
• Total formula weight: 41387.74

Authors

Rios-Steiner, J.L.,Murakami, M.T.,Tulinsky, A.,Arni, R.K. (deposition date: 2007-03-08, release date: 2007-11-06, Last modification date: 2011-07-13)

• Primary citation: Rios-Steiner, J.L.,Murakami, M.T.,Tulinsky, A.,Arni, R.K.; Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum; J.Mol.Biol., 371:774-786, 2007; PubMed: 17588602; DOI: 10.1016/j.jmb.2007.05.042

Experimental method

X-RAY DIFFRACTION (3.1 Å)