2OT1

Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with naphthol AS-E phosphate, a competitive inhibitor

2OT1 の概要

• エントリーDOI: 10.2210/pdb2ot1/pdb
• 分子名称: Fructose-bisphosphate aldolase A, N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE (3 entities in total)
• 機能のキーワード: glycolysis, competitive inhibition, hydrophobic pocket, lyase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 158565.55

構造登録者

St-Jean, M.,Izard, T.,Sygusch, J. (登録日: 2007-02-07, 公開日: 2007-02-27, 最終更新日: 2023-08-30)

• 主引用文献: St-Jean, M.,Izard, T.,Sygusch, J.; A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with wiskott-Aldrich syndrome protein.; J.Biol.Chem., 282:14309-14315, 2007; PubMed: 17329259; DOI: 10.1074/jbc.M611505200

実験手法

X-RAY DIFFRACTION (2.05 Å)