2OS5

Macrophage migration inhibitory factor from Ancylostoma ceylanicum

Summary for 2OS5

• Entry DOI: 10.2210/pdb2os5/pdb
• Descriptor: AceMIF, SULFATE ION (3 entities in total)
• Functional Keywords: macrophage migration inhibitory factor, cytokine, nematode, hookworm
• Biological source: Ancylostoma ceylanicum
• Total number of polymer chains: 4
• Total formula weight: 52948.85

Authors

Cho, Y.,Lolis, E. (deposition date: 2007-02-05, release date: 2007-06-12, Last modification date: 2024-02-21)

• Primary citation: Cho, Y.,Jones, B.F.,Vermeire, J.J.,Leng, L.,DiFedele, L.,Harrison, L.M.,Xiong, H.,Kwong, Y.K.,Chen, Y.,Bucala, R.,Lolis, E.,Cappello, M.; Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.; J.Biol.Chem., 282:23447-23456, 2007; PubMed: 17567581; DOI: 10.1074/jbc.M702950200

Experimental method

X-RAY DIFFRACTION (1.6 Å)