2OCI
Crystal structure of valacyclovir hydrolase complexed with a product analogue
Summary for 2OCI
| Entry DOI | 10.2210/pdb2oci/pdb |
| Related | 2OCG 2OCK 2OCL |
| Descriptor | Valacyclovir hydrolase, MANGANESE (II) ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | alpha beta hydrolase fold, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29130.53 |
| Authors | Lai, L.,Xu, Z.,Amidon, G.L. (deposition date: 2006-12-20, release date: 2008-02-05, Last modification date: 2023-08-30) |
| Primary citation | Lai, L.,Xu, Z.,Zhou, J.,Lee, K.D.,Amidon, G.L. Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283:9318-9327, 2008 Cited by PubMed: 18256025DOI: 10.1074/jbc.M709530200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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