2O53
Crystal structure of apo-Aspartoacylase from human brain
Summary for 2O53
Entry DOI | 10.2210/pdb2o53/pdb |
Related | 2O4H |
Descriptor | Aspartoacylase, ZINC ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | canavan disease, n-acetyl-l-aspartate, zinc-dependent hydrolase, aspartoacylase family, aminoacylase-2, acy2, aspa, n-phosphonomethyl-l-aspartate, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P45381 |
Total number of polymer chains | 2 |
Total formula weight | 72078.87 |
Authors | Le Coq, J.,Pavlovsky, A.,Sanishvili, R.,Viola, R.E. (deposition date: 2006-12-05, release date: 2007-11-06, Last modification date: 2023-08-30) |
Primary citation | Le Coq, J.,Pavlovsky, A.,Malik, R.,Sanishvili, R.,Xu, C.,Viola, R.E. Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47:3484-3492, 2008 Cited by PubMed: 18293939DOI: 10.1021/bi702400x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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