2O3X
Crystal Structure of the Prokaryotic Ribosomal Decoding Site Complexed with Paromamine Derivative NB30
Summary for 2O3X
Entry DOI | 10.2210/pdb2o3x/pdb |
Related | 2O3V 2O3W 2O3Y |
Descriptor | RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'), (1R,2R,3S,4R,6S)-4,6-DIAMINO-2-[(5-AMINO-5-DEOXY-BETA-D-RIBOFURANOSYL)OXY]-3-HYDROXYCYCLOHEXYL 2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE (2 entities in total) |
Functional Keywords | aminoglycoside, antibiotics, ribosome, decoding site, prokaryote, translation inhibition, stop codon readthrough, rna |
Total number of polymer chains | 2 |
Total formula weight | 15165.29 |
Authors | Kondo, J.,Hainrichson, M.,Nudelman, I.,Shallom-Shezifi, D.,Baasov, T.,Westhof, E. (deposition date: 2006-12-02, release date: 2007-11-06, Last modification date: 2023-08-30) |
Primary citation | Kondo, J.,Hainrichson, M.,Nudelman, I.,Shallom-Shezifi, D.,Barbieri, C.M.,Pilch, D.S.,Westhof, E.,Baasov, T. Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8:1700-1709, 2007 Cited by PubMed: 17705310DOI: 10.1002/cbic.200700271 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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