2O3X

Crystal Structure of the Prokaryotic Ribosomal Decoding Site Complexed with Paromamine Derivative NB30

2O3X の概要

• エントリーDOI: 10.2210/pdb2o3x/pdb
• 関連するPDBエントリー: 2O3V 2O3W 2O3Y
• 分子名称: RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'), (1R,2R,3S,4R,6S)-4,6-DIAMINO-2-[(5-AMINO-5-DEOXY-BETA-D-RIBOFURANOSYL)OXY]-3-HYDROXYCYCLOHEXYL 2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE (2 entities in total)
• 機能のキーワード: aminoglycoside, antibiotics, ribosome, decoding site, prokaryote, translation inhibition, stop codon readthrough, rna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15165.29

構造登録者

Kondo, J.,Hainrichson, M.,Nudelman, I.,Shallom-Shezifi, D.,Baasov, T.,Westhof, E. (登録日: 2006-12-02, 公開日: 2007-11-06, 最終更新日: 2023-08-30)

• 主引用文献: Kondo, J.,Hainrichson, M.,Nudelman, I.,Shallom-Shezifi, D.,Barbieri, C.M.,Pilch, D.S.,Westhof, E.,Baasov, T.; Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.; Chembiochem, 8:1700-1709, 2007; PubMed: 17705310; DOI: 10.1002/cbic.200700271

実験手法

X-RAY DIFFRACTION (2.9 Å)