2O3O

Crystal Structure of the sensor histidine kinase regulator YycI from Bacillus subtitlis

2O3O の概要

• エントリーDOI: 10.2210/pdb2o3o/pdb
• 分子名称: YycI protein, CHLORIDE ION (2 entities in total)
• 機能のキーワード: two-component system, signaling protein
• 由来する生物種: Bacillus subtilis
• 細胞内の位置: Cell membrane; Single-pass membrane protein (Potential): Q45612
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 355848.53

構造登録者

Santelli, E.,Liddington, R.C. (登録日: 2006-12-01, 公開日: 2007-04-10, 最終更新日: 2024-10-16)

主引用文献

Santelli, E.,Liddington, R.C.,Mohan, M.A.,Hoch, J.A.,Szurmant, H.
The Crystal Structure of Bacillus subtilis YycI Reveals a Common Fold for Two Members of an Unusual Class of Sensor Histidine Kinase Regulatory Proteins.
J.Bacteriol., 189:3290-3295, 2007

PubMed Abstract: YycI and YycH are two membrane-anchored periplasmic proteins that regulate the essential Bacillus subtilis YycG histidine kinase through direct interaction. Here we present the crystal structure of YycI at a 2.9-A resolution. YycI forms a dimer, and remarkably the structure resembles that of the two C-terminal domains of YycH despite nearly undetectable sequence homology (10%) between the two proteins.

PubMed: 17307848
DOI: 10.1128/JB.01937-06

実験手法

X-RAY DIFFRACTION (2.89 Å)