Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody CR1

Summary for 2NYY

DescriptorBotulinum neurotoxin type A, CR1 monoclonal antibody, ZINC ION, ... (5 entities in total)
Functional Keywordsbotulinum, neurotoxin, fab, protein antibody complex, toxin-immune system complex, toxin/immune system
Biological sourceHomo sapiens (human)
Cellular locationBotulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted P10845
Total number of polymer chains3
Total molecular weight197535.49
Stevens, R.C.,Arndt, J.W. (deposition date: 2006-11-21, release date: 2006-12-26, Last modification date: 2016-02-17)
Primary citation
Garcia-Rodriguez, C.,Levy, R.,Arndt, J.W.,Forsyth, C.M.,Razai, A.,Lou, J.,Geren, I.,Stevens, R.C.,Marks, J.D.
Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin.
Nat.Biotechnol., 25:107-116, 2007
PubMed: 17173035 (PDB entries with the same primary citation)
DOI: 10.1038/nbt1269
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.248142.3%6.1%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution