2NYY
Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody CR1
Summary for 2NYY
Entry DOI | 10.2210/pdb2nyy/pdb |
Related | 2NZ9 |
Descriptor | Botulinum neurotoxin type A, CR1 monoclonal antibody, ZINC ION, ... (5 entities in total) |
Functional Keywords | botulinum, neurotoxin, fab, protein antibody complex, toxin-immune system complex, toxin/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: P10845 |
Total number of polymer chains | 3 |
Total formula weight | 197535.49 |
Authors | Stevens, R.C.,Arndt, J.W. (deposition date: 2006-11-21, release date: 2006-12-26, Last modification date: 2023-08-30) |
Primary citation | Garcia-Rodriguez, C.,Levy, R.,Arndt, J.W.,Forsyth, C.M.,Razai, A.,Lou, J.,Geren, I.,Stevens, R.C.,Marks, J.D. Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin. Nat.Biotechnol., 25:107-116, 2007 Cited by PubMed: 17173035DOI: 10.1038/nbt1269 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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