2NXD

Structure of HIV-1 protease D25N complexed with rt-rh analogue peptide GLY-ALA-ASP-ILE-PHE*TYR-LEU-ASP-GLY-ALA

2NXD の概要

関連するPDBエントリー1KJG 2NXL 2NXM
分子名称PROTEASE RETROPEPSIN, Analogue of RT-RH pol protease substrate peptide (3 entities in total)
機能のキーワードpeptide design; molecular dynamics; hiv protease; substrate recognition; calorimetry, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate
由来する生物種HIV-1 M:B_ARV2/SF2
詳細
ポリマー鎖数3
分子量合計22670.72
構造登録者
Prabu-Jeyabalan, M.,Nalivaika, E.,Schiffer, C.A. (登録日: 2006-11-17, 公開日: 2007-09-18, 最終更新日: 2017-10-18)
主引用文献
Altman, M.D.,Nalivaika, E.A.,Prabu-Jeyabalan, M.,Schiffer, C.A.,Tidor, B.
Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease
Proteins, 70:678-694, 2007
PubMed: 17729291 (主引用文献が同じPDBエントリー)
DOI: 10.1002/prot.21514
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
?

構造検証レポート

ClashscoreRamachandran outliersSidechain outliers70.5%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード