2NSL

E. coli PurE H45N mutant complexed with CAIR

Summary for 2NSL

Related2ATE 2NSH 2NSJ
DescriptorPhosphoribosylaminoimidazole carboxylase catalytic subunit, 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID (3 entities in total)
Functional Keywordscentral three layer alpha-beta-alpha sandwich, kinked c-terminal helix, lyase
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight18114.42
Authors
Ealick, S.E.,Morar, M. (deposition date: 2006-11-04, release date: 2007-04-24, Last modification date: 2011-07-13)
Primary citation
Hoskins, A.A.,Morar, M.,Kappock, T.J.,Mathews, I.I.,Zaugg, J.B.,Barder, T.E.,Peng, P.,Okamoto, A.,Ealick, S.E.,Stubbe, J.
N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46:2842-2855, 2007
PubMed: 17298082 (PDB entries with the same primary citation)
DOI: 10.1021/bi602436g
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2229000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution