2NRJ

Crystal Structure of Hemolysin binding component from Bacillus cereus

2NRJ の概要

• エントリーDOI: 10.2210/pdb2nrj/pdb
• 分子名称: Hbl B protein (2 entities in total)
• 機能のキーワード: enterotoxin; hemolysis; transmembrane, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, toxin
• 由来する生物種: Bacillus cereus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38934.70

構造登録者

Madegowda, M.,Eswaramoorthy, S.,Burley, S.K.,Swaminathan, S.,New York SGX Research Center for Structural Genomics (NYSGXRC) (登録日: 2006-11-02, 公開日: 2006-11-14, 最終更新日: 2024-10-30)

主引用文献

Madegowda, M.,Eswaramoorthy, S.,Burley, S.K.,Swaminathan, S.
X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus
Proteins, 71:534-540, 2008

PubMed Abstract: Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.

PubMed: 18175317
DOI: 10.1002/prot.21888

実験手法

X-RAY DIFFRACTION (2.03 Å)