2NLK

Crystal structure of D1 and D2 catalytic domains of human Protein Tyrosine Phosphatase Gamma (D1+D2 PTPRG)

2NLK の概要

• エントリーDOI: 10.2210/pdb2nlk/pdb
• 分子名称: Protein tyrosine phosphatase, receptor type, G variant (Fragment) (2 entities in total)
• 機能のキーワード: ptprg, r-ptp gamma, protein tyrosine phosphatase gamma, d3s1249, hptpg, rptpg, ptpg, d1-d2 catalytic domains, structural genomics, structural genomics consortium, sgc, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71766.34

構造登録者

Filippakopoulos, P.,Gileadi, O.,Johansson, C.,Ugochukwu, E.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2006-10-20, 公開日: 2006-11-21, 最終更新日: 2023-08-30)

• 主引用文献: Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.; Large-scale structural analysis of the classical human protein tyrosine phosphatome.; Cell(Cambridge,Mass.), 136:352-363, 2009; PubMed: 19167335; DOI: 10.1016/j.cell.2008.11.038

実験手法

X-RAY DIFFRACTION (2.4 Å)