2MZX
CCR5-ECL2 helical structure, residues Q186-T195
Summary for 2MZX
Entry DOI | 10.2210/pdb2mzx/pdb |
NMR Information | BMRB: 25505 |
Descriptor | C-C chemokine receptor type 5 (1 entity in total) |
Functional Keywords | signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane ; Multi-pass membrane protein : P51681 |
Total number of polymer chains | 1 |
Total formula weight | 1390.52 |
Authors | Abayev, M.,Anglister, J. (deposition date: 2015-02-26, release date: 2015-04-22, Last modification date: 2024-05-15) |
Primary citation | Abayev, M.,Moseri, A.,Tchaicheeyan, O.,Kessler, N.,Arshava, B.,Naider, F.,Scherf, T.,Anglister, J. An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions. Febs J., 282:1906-1921, 2015 Cited by PubMed: 25703038DOI: 10.1111/febs.13243 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report