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2MWO

Solution structure of 53BP1 tandem Tudor domains in complex with a p53K370me2 peptide

Summary for 2MWO
Entry DOI10.2210/pdb2mwo/pdb
Related2MWP
NMR InformationBMRB: 25347
DescriptorTumor suppressor p53-binding protein 1, Cellular tumor antigen p53 (2 entities in total)
Functional Keywordscell cycle, dna damage response, transcription-antitumor protein complex, transcription/antitumor protein
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: Q12888
Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
Total number of polymer chains2
Total formula weight15629.70
Authors
Cui, G.,Botuyan, M.V.,Mer, G. (deposition date: 2014-11-15, release date: 2014-12-10, Last modification date: 2015-03-18)
Primary citationTong, Q.,Cui, G.,Botuyan, M.V.,Rothbart, S.B.,Hayashi, R.,Musselman, C.A.,Singh, N.,Appella, E.,Strahl, B.D.,Mer, G.,Kutateladze, T.G.
Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23:312-321, 2015
Cited by
PubMed: 25579814
DOI: 10.1016/j.str.2014.11.013
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

数据于2024-03-27公开中

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