The structure of the carboxy-terminal domain of DNTTIP1

Summary for 2MWI

DescriptorDeoxynucleotidyltransferase terminal-interacting protein 1 (1 entity in total)
Functional Keywordshdac, histone deacetylase, gene expression, dnttip1, mideas, hdac1, tdif1, protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9H147
Total number of polymer chains1
Total molecular weight14060.2
Schwabe, J.W.R.,Muskett, F.W.,Itoh, T. (deposition date: 2014-11-11, release date: 2015-02-18, Last modification date: 2015-03-18)
Primary citation
Itoh, T.,Fairall, L.,Muskett, F.W.,Milano, C.P.,Watson, P.J.,Arnaudo, N.,Saleh, A.,Millard, C.J.,El-Mezgueldi, M.,Martino, F.,Schwabe, J.W.
Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43:2033-2044, 2015
PubMed: 25653165 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkv068
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers101.7%36.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload