Solution structure of the transmembrane domain and the juxta-membrane domain of the Erythropoietin Receptor in micelles

Summary for 2MV6

DescriptorErythropoietin receptor (1 entity in total)
Functional Keywordsmicelles, transmembrane domain, erythropoietin receptor, membrane protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted  P19235
Total number of polymer chains1
Total molecular weight5448.7
Li, Q.,Wong, Y.,Huang, Q.,Kang, C. (deposition date: 2014-09-23, release date: 2014-12-10)
Primary citation
Li, Q.,Wong, Y.L.,Huang, Q.,Kang, C.
Structural insight into the transmembrane domain and the juxtamembrane region of the erythropoietin receptor in micelles.
Biophys.J., 107:2325-2336, 2014
PubMed: 25418301 (PDB entries with the same primary citation)
DOI: 10.1016/j.bpj.2014.10.013
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers2026.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2mv6
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Molmil generated image of 2mv6
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