2MPT
WW3 domain of Nedd4L in complex with its HECT domain PY motif
Summary for 2MPT
Entry DOI | 10.2210/pdb2mpt/pdb |
NMR Information | BMRB: 25000 |
Descriptor | E3 ubiquitin-protein ligase NEDD4-like (2 entities in total) |
Functional Keywords | ww, nedd4l, nedd4.2, hect, py, ww3, auto-ubiquitination, proteasomal degradation, ubiquitin ligase, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q96PU5 Q96PU5 |
Total number of polymer chains | 2 |
Total formula weight | 7272.28 |
Authors | Escobedo, A.,Macias, M.J.,Gomes, T.,Aragon, E.,Martin-Malpartida, P.,Ruiz, L. (deposition date: 2014-06-02, release date: 2014-10-22) |
Primary citation | Escobedo, A.,Gomes, T.,Aragon, E.,Martin-Malpartida, P.,Ruiz, L.,Macias, M.J. Structural Basis of the Activation and Degradation Mechanisms of the E3 Ubiquitin Ligase Nedd4L. Structure, 22:1446-1457, 2014 Cited by PubMed: 25295397DOI: 10.1016/j.str.2014.08.016 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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