2MLQ

Human CCR2 Membrane-Proximal C-Terminal Region (PRO-C) in a frount bound form

Summary for 2MLQ

Related2MLO
DescriptorMCP-1 receptor (1 entity in total)
Functional Keywordsccr2, pro-c, frount, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Multi-pass membrane protein (By similarity) O95950
Total number of polymer chains1
Total molecular weight2133.54
Authors
Esaki, K.,Yoshinaga, S.,Tsuji, T.,Toda, E.,Terashima, Y.,Saitoh, T.,Kohda, D.,Kohno, T.,Osawa, M.,Ueda, T.,Shimada, I.,Matsushima, K.,Terasawa, H. (deposition date: 2014-03-04, release date: 2014-10-08, Last modification date: 2014-10-29)
Primary citation
Esaki, K.,Yoshinaga, S.,Tsuji, T.,Toda, E.,Terashima, Y.,Saitoh, T.,Kohda, D.,Kohno, T.,Osawa, M.,Ueda, T.,Shimada, I.,Matsushima, K.,Terasawa, H.
Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT
Febs J., 2014
PubMed: 25283965 (PDB entries with the same primary citation)
DOI: 10.1111/febs.13096
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers22.0%39.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

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