2MI5
Structure of insect-specific sodium channel toxin mu-Dc1a
Summary for 2MI5
| Entry DOI | 10.2210/pdb2mi5/pdb |
| NMR Information | BMRB: 19666 |
| Descriptor | Mu-diguetoxin-Dc1a (1 entity in total) |
| Functional Keywords | spider venom, insecticidal toxin, sodium channel, voltage-sensor, gating modifier, non-uniform sampling, dtx9.2, toxin, inhibitor cystine knot, knottin |
| Biological source | Diguetia canities (Desert bush spider) |
| Cellular location | Secreted: P49126 |
| Total number of polymer chains | 1 |
| Total formula weight | 6502.44 |
| Authors | Bende, N.S.,Mobli, M.,King, G.F. (deposition date: 2013-12-08, release date: 2014-07-23, Last modification date: 2023-06-14) |
| Primary citation | Bende, N.S.,Dziemborowicz, S.,Mobli, M.,Herzig, V.,Gilchrist, J.,Wagner, J.,Nicholson, G.M.,King, G.F.,Bosmans, F. A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nat Commun, 5:4350-4350, 2014 Cited by PubMed: 25014760DOI: 10.1038/ncomms5350 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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