2MHZ

Structure of Exocyclic S,S N6,N6-(2,3-Dihydroxy-1,4-butadiyl)-2'-Deoxyadenosine Adduct Induced by 1,2,3,4-Diepoxybutane in DNA

2MHZ の概要

• エントリーDOI: 10.2210/pdb2mhz/pdb
• NMR情報: BMRB: 19661
• 分子名称: 5'-D(*CP*GP*GP*AP*CP*(SDE)P*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3' (2 entities in total)
• 機能のキーワード: b-form dna, 11-mer, deb induced adduct, dhb-da adduct, n-ras codon 61 sequence, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6795.51

構造登録者

Kowal, E.A.,Seneviratne, U.,Wickramaratne, S.,Doherty, K.E.,Cao, X.,Tretyakova, N.,Stone, M.P. (登録日: 2013-12-05, 公開日: 2014-05-28, 最終更新日: 2024-05-01)

• 主引用文献: Kowal, E.A.,Seneviratne, U.,Wickramaratne, S.,Doherty, K.E.,Cao, X.,Tretyakova, N.,Stone, M.P.; Structures of Exocyclic R,R- and S,S-N(6),N(6)-(2,3-Dihydroxybutan-1,4-diyl)-2'-Deoxyadenosine Adducts Induced by 1,2,3,4-Diepoxybutane.; Chem.Res.Toxicol., 27:805-817, 2014; PubMed: 24741991; DOI: 10.1021/tx400472p

実験手法

SOLUTION NMR