2MHA

CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION

2MHA の概要

• エントリーDOI: 10.2210/pdb2mha/pdb
• 分子名称: CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU (3 entities in total)
• 機能のキーワード: histocompatibility antigen
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 87502.19

構造登録者

Zhang, W.,Young, A.C.M.,Imarai, M.,Nathenson, S.G.,Sacchettini, J.C. (登録日: 1993-07-21, 公開日: 1993-10-31, 最終更新日: 2019-08-14)

• 主引用文献: Zhang, W.,Young, A.C.,Imarai, M.,Nathenson, S.G.,Sacchettini, J.C.; Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.; Proc.Natl.Acad.Sci.USA, 89:8403-8407, 1992; PubMed: 1325657; DOI: 10.1073/pnas.89.17.8403

実験手法

X-RAY DIFFRACTION (2.5 Å)