2M8D

Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'

Summary for 2M8D

• Entry DOI: 10.2210/pdb2m8d/pdb
• NMR Information: BMRB: 19248
• Descriptor: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1 (2 entities in total)
• Functional Keywords: sr protein, pseudo-rrm, rrm, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q07955
• Total number of polymer chains: 2
• Total formula weight: 12928.23

Authors

Clery, A.,Sinha, R.,Anczukow, O.,Corrionero, A.,Moursy, A.,Daubner, G.,Valcarcel, J.,Krainer, A.R.,Allain, F.H.T. (deposition date: 2013-05-17, release date: 2013-07-10, Last modification date: 2023-06-14)

• Primary citation: Clery, A.,Sinha, R.,Anczukow, O.,Corrionero, A.,Moursy, A.,Daubner, G.M.,Valcarcel, J.,Krainer, A.R.,Allain, F.H.; Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.; Proc.Natl.Acad.Sci.USA, 110:E2802-E2811, 2013; PubMed: 23836656; DOI: 10.1073/pnas.1303445110

Experimental method

SOLUTION NMR