2M7P
RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation
Summary for 2M7P
Entry DOI | 10.2210/pdb2m7p/pdb |
NMR Information | BMRB: 19200 |
Descriptor | Low-density lipoprotein receptor, Relaxin receptor 1, CALCIUM ION (2 entities in total) |
Functional Keywords | rxfp1, relaxin, ldla, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 4590.05 |
Authors | Kong, R.CK.,Petrie, E.J.,Mohanty, B.,Ling, J.,Lee, J.C.Y.,Gooley, P.R.,Bathgate, R.A.D. (deposition date: 2013-04-29, release date: 2013-08-14, Last modification date: 2023-06-14) |
Primary citation | Kong, R.C.K.,Petrie, E.J.,Mohanty, B.,Ling, J.,Lee, J.C.,Gooley, P.R.,Bathgate, R.A.D. The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation. J.Biol.Chem., 288:28138-28151, 2013 Cited by PubMed: 23926099DOI: 10.1074/jbc.M113.499640 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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