2M6X
Structure of the p7 channel of Hepatitis C virus, genotype 5a
Summary for 2M6X
| Entry DOI | 10.2210/pdb2m6x/pdb |
| NMR Information | BMRB: 19162 |
| Descriptor | p7 (1 entity in total) |
| Functional Keywords | membrane protein, cation channel |
| Biological source | Hepatitis C virus (HCV) |
| Cellular location | Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein (By similarity). Core protein p19: Virion (By similarity). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p7: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): O39928 |
| Total number of polymer chains | 6 |
| Total formula weight | 40572.44 |
| Authors | OuYang, B.,Chou, J.J. (deposition date: 2013-04-12, release date: 2013-06-12, Last modification date: 2014-01-29) |
| Primary citation | OuYang, B.,Xie, S.,Berardi, M.J.,Zhao, X.,Dev, J.,Yu, W.,Sun, B.,Chou, J.J. Unusual architecture of the p7 channel from hepatitis C virus Nature, 498:521-525, 2013 Cited by PubMed: 23739335DOI: 10.1038/nature12283 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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