2M36

Solution structure of the insecticidal spider-venom peptide Aps III

Summary for 2M36

• Entry DOI: 10.2210/pdb2m36/pdb
• NMR Information: BMRB: 18946
• Descriptor: U2-cyrtautoxin-As1a (1 entity in total)
• Functional Keywords: asp iii, mu-cutx-as1a, inhibitor cystine knot, voltage-gated sodium channel, insect toxin, toxin
• Biological source: Apomastus schlingeri (Trap-door spider)
• Cellular location: Secreted: P49268
• Total number of polymer chains: 1
• Total formula weight: 3859.33

Authors

King, G.F.,Bende, N.S.,Mobli, M. (deposition date: 2013-01-10, release date: 2013-03-27, Last modification date: 2023-06-14)

• Primary citation: Bende, N.S.,Kang, E.,Herzig, V.,Bosmans, F.,Nicholson, G.M.,Mobli, M.,King, G.F.; The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels.; Biochem Pharmacol, 85:1542-1554, 2013; PubMed: 23473802; DOI: 10.1016/j.bcp.2013.02.030

Experimental method

SOLUTION NMR